In the past, Placenta substances have been used successfully for the treatment of wounds, i.e. for renewal of damaged skin cell tissue. They are now also used to treat various other skin disorders, such as ulsus cruris, psoriasis and urticaria. This substance is most effective in the treatment of skin damage, arising from deficient blood flow and degeneration of the cells (aging skin). They stimulate cell renewals in living human skin and increase the blood flow in the vessels, revitalizing the skin.